Chapter 4
Page 18.1

Black Box Warning for Abilify, Seroquel and Clozapine

Black Box Warning for Abilify and Seroquel

The Physician Desk Reference documents the black box warning for Abilify and Seroquel:

  • “Not approved for depression in under age 18. Increased the risk of suicidal thinking and behavior in short-term studies in children and adolescents with major depressive disorder and other psychiatric disorders”

Black Box Warning for Clozapine

The Physician Desk Reference documents the black box warning for Clozapine:

  • Risk of life threatening agranulocytosis
  • Seizures
  • Myocarditis
  • Other adverse cardiovascular and respiratory effects